Xingjian Zhang

PhD Candidate & Research Engineer in AI for Biomedical Imaging
Paris, FR.

About

PhD Candidate in AI for Biomedical Imaging, specializing in self-supervised learning and generative models for advanced image restoration and analysis. Proven ability to translate cutting-edge research into practical solutions, evidenced by contributions to high-impact publications (Science Advances, Communications Biology) and successful deployment of deep learning models in industry settings. Eager to leverage expertise in machine learning, computer vision, and bioimaging to drive innovation in a research-focused or advanced engineering role.

Work

LadHyX, École Polytechnique & LTCI, Télécom Paris
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PhD Candidate

Paris, Île-de-France, France

Summary

Leading advanced deep learning research to develop end-to-end ML pipelines for quantifying cellular nuclear deformations in microscopy imaging, enabling in-vitro diagnostics for laminopathies and breast cancer.

Dassault Systèmes
|

Research Engineer Intern

Paris, Île-de-France, France

Summary

Developed and deployed advanced 3D deep learning models for automated tumor segmentation on volumetric CT scans, leveraging multi-GPU clusters for large-scale experimentation in a production environment.

LOB, École Polytechnique
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Research Intern

Paris, Île-de-France, France

Summary

Developed advanced segmentation algorithms and optimized computational workflows for pSHG and THG microscopy imaging, contributing to cutting-edge research in bioimage analysis.

Education

École Polytechnique
Paris, Île-de-France, France

PhD

Biomedical Engineering (AI for Biomedical Imaging)

École Polytechnique
Paris, Île-de-France, France

MSc

Biomedical Engineering

École Polytechnique
Paris, Île-de-France, France

BSc

Mathematics and Computer Science

Grade: 4.0

Projects

Automated Hot Flash Detection (Elocare/NUS)

Summary

Led machine learning development for automated hot flash detection using skin conductance data in collaboration with Elocare and NUS, Singapore.

ML Models for Electrical Impedance Spectroscopy in Cellular Monitoring (Sensome)

Summary

Developed machine learning models for analyzing electrical impedance spectroscopy data to monitor cellular activity in collaboration with Sensome.

BioImageLoader

Summary

Developed an open-source Python library for efficient, large-scale bioimage data loading, optimizing machine learning pipeline performance.

Publications

Log focal frequency loss for bioimage restoration

Published by

IEEE International Symposium on Biomedical Imaging (ISBI)

Summary

First-authored research on the development of a novel loss function for enhanced bioimage restoration, presentation at a leading international symposium.

Label-free multimodal non-linear microscopy to probe metabolism and myelin distribution

Published by

Communications Biology

Summary

Collaborative study investigating label-free multimodal non-linear microscopy techniques to analyze metabolism and myelin distribution in biological samples.

Noninvasive real-time monitoring of cellular spatiotemporal dynamics via machine learning-enhanced electrical impedance spectroscopy

Published by

Science Advances

Summary

Collaborative research on developing a machine learning-enhanced method for noninvasive, real-time monitoring of cellular spatiotemporal dynamics using electrical impedance spectroscopy.

Changes in ascending aorta and aortic arch secondary flow patterns following endovascular repair

Published by

European Journal of Vascular and Endovascular Surgery

Summary

Collaborative study analyzing changes in ascending aorta and aortic arch secondary flow patterns after endovascular repair procedures.

Microscale topography triggers dynamic 3D nuclear deformations

Published by

Advanced Science

Summary

Collaborative research demonstrating how microscale topography influences dynamic 3D nuclear deformations in cells, published in a high-impact journal.

Myoblast mutation classification via microgroove-induced nuclear deformations

Published by

Medical Imaging with Deep Learning (MIDL)

Summary

First-authored research focusing on classifying myoblast mutations through deep learning analysis of microgroove-induced nuclear deformations.

Modeling and predicting second harmonic generation from protein molecular structure

Published by

Physical Review X

Summary

Collaborative work on developing models to predict second harmonic generation signals directly from protein molecular structures.

Skills

Machine Learning & Deep Learning

PyTorch, JAX, TensorFlow, Self-supervised Learning, Generative Models, Deep Learning, Computer Vision, Multi-GPU Training.

Programming Languages

Python, Julia, R, Matlab, C/C++, JavaScript, HTML/CSS.

MLOps & Development Tools

Git, Docker, PySpark, SQL, Pandas.

Bioimaging & Medical Imaging

NIS-Elements, ImageJ/FIJI, Icy, CellProfiler, ITK, 3D Slicer, Imaris, ParaView, MONAI, DICOM, NIFTI, HDF5, ND2 formats, Image Restoration, Tumor Segmentation, Microscopy.

Research & Analysis

Biomedical Imaging, Cellular Mechanics, Data Analysis, Scientific Writing, Statistical Modeling.

Languages

Chinese

Native

English

Native

French

Proficient